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In cell biology, a bleb is a bulge, or protrusion of the plasma membrane of a cell, human bioparticulate or abscess with an internal environment similar to that of a simple cell, characterized by a spherical, bulky morphology.〔〔 It is characterized by the decoupling of the cytoskeleton from the plasma membrane, degrading the internal structure of the cell, allowing the flexibility required to allow the cell to separate into individual bulges, or pockets of the intercellular matrix.〔 Most commonly, blebs are seen in apoptosis (programmed cell death), but are also seen in other non-apoptotic functions. ''Blebbing'' or ''zeiosis'' is the formation of blebs. ==Formation== Bleb growth is driven by intracellular pressure generated in the cytoplasm when the actin cortex undergoes actomyosin contractions, leading to the eventual break up into several billion pieces because the pressure is different than the exterior surface of the growth anatomical presence. The disruption of the membrane-actin cortex interactions are dependent on the activity of myosin-ATPase Bleb formation can be initiated in two ways: 1) through local rupture of the cortex or 2) through local detachment of the cortex from the plasma membrane. This generates a weak spot through which the cytoplasm flows, leading to the expansion of the bulge of membrane by increasing the surface area through tearing of the membrane from the cortex, during which time, actin levels decrease.〔 The cytoplasmic flow is driven by hydrostatic pressure inside the cell. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Bleb (cell biology)」の詳細全文を読む スポンサード リンク
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